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Bowwowmeow
02-27-2007, 09:28 PM
Study: Garlic Won't Lower Cholesterol


By LINDSEY TANNER (AP Medical Writer)
From Associated Press
February 27, 2007 9:31 PM EST
CHICAGO - Garlic doesn't do much for the breath and it stinks for lowering cholesterol. That's the conclusion of the most rigorous, head-to-head study of raw garlic and popular garlic supplements, despite promoters' claims to the contrary.
Whether it was eaten raw in heart-healthy sandwiches, or in pills made of powdered or aged garlic, the strong-smelling herb had no effect on cholesterol in people whose levels were already elevated, the government-funded study found.
"If garlic was going to have a chance to work, it would have worked in this study," said researcher Christopher Gardner. But it didn't.
Garlic is a longtime folk remedy for a variety of ills, including heart disease, cancer, infections and even mosquito bites. Scientific research on its purported benefits has had conflicting results. Some previous studies suggested garlic might help lower risks for digestive and prostate cancers, or might reduce blood pressure and cholesterol levels; others found no benefit.
Health benefits have been thought to come from a sulfur-containing substance called allicin that is released when raw garlic is chopped or crushed. In lab tests, it can be applied directly to cells and has been shown to prevent cholesterol production.
But any direct benefits to the body from allicin may be diluted when garlic is eaten, said Gardner, an assistant professor of medicine at Stanford University.
Still, Gardner, a garlic lover, was optimistic when he and colleagues began their study. He called the results disappointing but said it's still possible garlic might improve cholesterol when eaten in bigger doses or by people with more severe cholesterol problems. Also, garlic could have characteristics other than influencing cholesterol that might benefit the heart, he said.
The study appears in Monday's Archives of Internal Medicine.
An Archives editorial agreed and said "the jury is still out" on whether garlic might prevent cardiovascular disease.
The study involved 192 adults aged about 50 on average with moderately elevated levels of LDL cholesterol, the bad kind that contributes to heart disease. The average LDL level was 140 milligrams per deciliter of blood, or in the borderline-high range. Below 100 is considered ideal.
Participants were randomly assigned to eat the equivalent of an average clove of garlic in either raw form or garlic pills, or dummy pills, six days weekly for six months.
Raw garlic was mixed into salsa, fat-free mayonnaise or other condiments spread on portobello mushroom sandwiches, chicken quesadillas and other specialty sandwiches. Participants in the garlic pill and dummy pill groups also got sandwiches, but without garlic.
Bad breath and body odor were reported by more than half the raw garlic eaters, and a handful of people in the supplement groups reported flatulence, but there were no major side effects. There also was virtually no effect on cholesterol levels in any of the groups.
Blood samples were taken monthly to detect any changes in cholesterol readings but found none that were statistically significant. Diet and exercise levels also were monitored to detect any changes that could affect cholesterol levels.
Robert Borris, a scientist with the Council for Responsible Nutrition, a trade group for nutritional supplement makers, said the study doesn't answer whether garlic might help regulate cholesterol levels in healthy people.
The results also don't refute scientific evidence suggesting that garlic can reduce the tendency of blood platelets to build up and form clots that could block arteries, Borris said.
"I certainly would not give up on garlic," he said.

"Raw garlic was ... spread on ...chicken quesadillas and other specialty sandwiches."
F*cking idiots. They spent six months giving people slabs of cholesterol and saturated fat-ridden dead animal sprinkled with a little garlic, and then decide garlic doesn't work. :dunce:

You know, I have a problem these people might like to study. I keep hitting myself over the head with a hammer, for no good reason, and no matter how much arnica ointment I put on the bruise, it keeps on hurting every time I hit myself again. I guess arnica is no good either. :rolleyes:

Garlic has lots of health benefits, which I will look up and post here (I'm looking into materials for the health benefits of all sorts of foods to have here), but I don't care if it lowers cholesterol or not, since I don't eat cholesterol. A small number of people have genetic liver problems that keep their cholesterol levels unhealthy. I wonder if they bother to find people like this, make sure they eat no cholesterol or saturated fat, and see if garlic will help them. I might actually believe the results of such research, depending of course upon who paid for it.

At least the FDA can't ban garlic sales.

Oracl
02-27-2007, 09:51 PM
F*cking idiots. :dunce:
Yep, that's for sure! :crazy: That study was a WOFTAM. :rolleyes: :grumble:

paul
02-28-2007, 12:17 AM
Mmmm garlic, stuuupppiiid people:hbang:

thevegantwins
02-28-2007, 06:12 AM
Bowwowmeow, I'm one of those people who have naturally high cholesterol, I hover around 230. The doctors have tried to push statin drugs on me for years. I did take them for a bit in my 20's but then I stopped because I don't feel like enduring liver damage due to the drugs. I've been eating 1/2 clove a garlic a day, at minimum for the past 6 months plus regular garlic intake for years. I'd be curious to know why my cholesterol levels are now.

My first thought when I saw that study online yesterday was that the doctors probably worked for Merck or Pfizer, any one of the companies who make statin drugs.

Gliondrach
02-28-2007, 07:05 AM
There was an experiment shown on television a few months ago which had volunteers eating three or four cloves of garlic a day. They all saw the benefits on their health. I'm not sure now if this was lowered cholesterol or blood pressure.

Of course, in any trial like this, the dose is important. I know that drug company-inspired trials often deliberately choose the wrong dose.

Charmagne
02-28-2007, 08:22 PM
I'm with TVT - I'm still inclined to say that this test was at least funded by one of the drug companies whose major drugs are statins.

I love garlic - and now this had made me want spaghetti - which I'll cook tomorrow with plenty of garlic!:agree:

my3labs
02-28-2007, 09:21 PM
"Raw garlic was ... spread on ...chicken quesadillas and other specialty sandwiches."

Super geniuses! I agree...it was probably sponsored by some dead animal or drug company.

Gliondrach
03-03-2009, 09:54 AM
Or they could just give up animal products. Then, the only cholesterol they'll have is what they make themselves.

02-23-09

Yeon-Kyun Shin, Biochemistry, Biophysics and Molecular Biology, (515) 294-2530,

Dan Kuester, News Service, 515-294-0704

Cholesterol-reducing drugs may lessen brain function, says ISU researcher
AMES, Iowa -- Research by an Iowa State University scientist suggests that
cholesterol-reducing drugs known as statins may lessen brain function.

Yeon-Kyun Shin, a biophysics professor in the department of biochemistry, biophysics and
molecular biology, says the results of his study show that drugs that inhibit the liver from making cholesterol may also keep the brain from making cholesterol, which is vital to efficient brain function.

"If you deprive cholesterol from the brain, then you directly affect the machinery that triggers the release of neurotransmitters," said Shin. "Neurotransmitters affect the data-processing and
memory functions. In other words -- how smart you are and how well you remember things."

Shin's findings will be published in this month's edition of the journal Proceedings of the National Academy of Sciences of the United States of America.

Cholesterol is one of the building blocks of cells and is made in the liver. Low-density
lipoprotein (LDL) -- often referred to as bad cholesterol -- is cholesterol in the bloodstream from the liver on the way to cells in the body. High-density lipoprotein (HDL) -- so-called good
cholesterol -- is cholesterol being removed from cells. Too much LDL going to cells and not
enough being removed can lead to cholesterol deposits and hardening of the cells.

"If you have too much cholesterol, your internal machinery is not going to be able to take away
enough cholesterol from the cells," said Shin. "Then cells harden and you can get these
deposits."

Cholesterol-reducing statin drugs are helpful because they keep the liver from synthesizing
cholesterol so less of the substance is carried to the cells. This lowers LDL cholesterol.

It is the function of reducing the synthesis of cholesterol that Shin's study shows may also harm brain function.

"If you try to lower the cholesterol by taking medicine that is attacking the machinery of
cholesterol synthesis in the liver, that medicine goes to the brain too. And then it reduces the
synthesis of cholesterol which is necessary in the brain," said Shin.

In his experiments, Shin tested the activity of the neurotransmitter-release machinery from brain cells without cholesterol present and measured how well the machinery functioned. He then included cholesterol in the system and again measured the protein function. Cholesterol
increased protein function by five times.

"Our study shows there is a direct link between cholesterol and the neurotransmitter release,"
said Shin. "And we know exactly the molecular mechanics of what happens in the cells.
Cholesterol changes the shape of the protein to stimulate thinking and memory."

While reducing the cholesterol in the brain may make you have less memory and cognitive
skills, more cholesterol in the blood does not make people smarter. Because cholesterol in the
blood cannot get across the blood brain barrier, there is no connection to the amount of
cholesterol a person eats and brain function.

Shin says that for many people taking cholesterol-lower statins can be very healthful and they
should listen to their doctor when taking medication.
public.iastate.edu/~nscentral/news/2009/feb/shin.shtml

Gliondrach
03-03-2009, 10:14 AM
I'm with TVT - I'm still inclined to say that this test was at least funded by one of the drug companies whose major drugs are statins.



The drug-pusher companies like to twist things to make their own products look good. See:
http://www.thenakedvegan.net/showthread.php?p=59577#post59577 post 127.

gibby
07-10-2009, 08:19 AM
There are plenty of studies that show how good raw garlic can be

Ive always eaten 2 raw cloves a day & personally I love the smell.
For those that dont like it so much eat a bit of fresh parsley afterwards as its kills off the smell

If I get a cold I do the following & it burns even the worst colds & flu out of the body

Juice or blend in equal quantities

raw organic garlic
ginger root
hot peppers - any type
horseraddish root
white onion
organic cider apple vinegar

It keeps in the fridge for over a year & con be frozen

as soon as you feel a cold or sore throat put a small amount in a glass & sip it. Gargle if you can

Its also good for a detox as your body will start sweating.

G

Gliondrach
07-10-2009, 03:14 PM
Seems like a good tip. I'll give it a try next time I get any sniffles. But I rarely get a full cold - I will get the beginnings of a sore-ish throat or a stuffy nose but the next day I will be back to full health.

gibby
07-13-2009, 09:31 AM
forgot to mention

its very powerful & may make you dance around the kitchen on the first taste
but you get used to it

would make a good video on u tube

G

Gliondrach
07-13-2009, 09:42 AM
I often dance around the kitchen - especially when I'm handling very hot toast.